Ascendant Diagnostics
Ascendant-Diagnostics.com
Ascendant Diagnostics is developing innovative new approaches to the improved diagnosis of serious diseases and conditions. Its first product is a non-invasive test for early stage diagnosis of breast cancer. Approximately 240,000 women are diagnosed with breast cancer each year in the U.S. and the total economic burden of treatment is about $40 billion. However, survival rates are greatly enhanced and treatment costs are much lower when breast cancer is treated at an early stage. Improved diagnostic tests that are simple, reliable and non-invasive could save many lives by detecting the breast cancer earlier. Ascendant Diagnostics’ breast cancer detection technology is aimed at this critical unmet need.



BioDetection Instruments
Biodetection-Instruments.com
The mission of BioDetection Instruments is to improve the safety and quality of the world's food supply by providing the highest performance biosensors, assay kits and instruments for rapid detection of food pathogens and chemical residues. The company’s Aegis™ biosensor system provides an unparalleled combination of low detection limits (down to 10 cells/mL) and speed (1 hour) for the identification and quantification of pathogenic bacteria in food and drinks.



BiologicsMD
BiologicsMD.com
The risk of a woman over the age of fifty dying from an osteoporosis-related fracture is greater than the risk of her dying from breast, uterine, and ovarian cancer combined. BiologicsMD is developing a new prescription osteoporosis solution based on a unique patent-pending compound that binds to bone and stimulates new bone growth thereby reversing osteoporosis. Pre-clinical animal studies demonstrate that it is three times more effective at increasing bone density than the leading medication with no observed side effects. 2008 revenues for prescription osteoporosis medications exceeded $9 billion globally and $2 billion in the U.S.



BlueInGreen
BlueInGreen.com
BlueInGreen offers equipment that incorporates an innovative new approach for cost effective dissolved oxygen delivery. The supersaturated dissolved oxygen (or SDOX™) systems offer low capital and operating costs, precisely controlled delivery of dissolved oxygen at a wide range of target concentrations, ease of operation, and virtually 100% gas utilization efficiency (no off-gassing) for wastewater treatment and other environmental water applications. Up to 80% operating cost savings have been documented as compared to conventional oxygen delivery technology.



CardioWise
CardioWise.co
Cardiovascular disease is the leading cause of death for men and women in the United States and kills 2,400 Americans every day (1 every 37 seconds). It is estimated that 80,700,000 Americans (1 in 3) have some form of cardiovascular disease. CardioWise is developing new approaches to cardiac health monitoring and care. Its first product is a new cardiac imaging modality that:

• allows all images to be acquired in a single one-hour appointment;
• requires no exposure to intravenous contrast, dobutamine, dipyridamole, or ionizing radiation;
• produces images of cardiac contractile function throughout the thickness of the left ventricle as opposed to just the surface;
• delivers quantitative, detailed, and easily interpreted, color coded images; and
• enables direct, quantified comparison of data from an individual acquired at different times.

The quality of the produced images is dramatically superior to that of competing technologies. This innovative technology can provide early warning with reduced incidence of irreversible myocardial damage or death in previously asymptomatic individuals.



GeneFab
GeneFab is developing innovative uses of DNA oligonucleotides and nanomaterials for a wide range of applications, including cancer therapeutics, biomedical devices, DNA memory and computing.



Minotaur Technologies
Minotaur Technologies is a biophotonics company whose mission is to develop new laser-based instrumentation for life sciences research. The company is developing instruments that are applicable to a broad range of cell biology problems in neuroscience and beyond, including chemotaxis, stem-cell differentiation and in vitro testing of cellular response to emerging treatments.



NanoMech
NanoMech.biz
NanoMech is a designer and manufacturer of innovative application specific nanoparticle additives, nanoparticle-based coatings and coating deposition systems that can be used in a variety of critical industry sectors. Many of the company's key products are based on a patented technology that allows very small particles to be applied to surfaces in coating form, creating coatings that have extremely beneficial properties. In the coating process the individual particles, known as nanoparticles, can be 1,000 to 10,000 times smaller than the thickness of a human hair. These nanocoatings can be engineered to have valuable properties such as extreme wear resistance, self-lubrication, corrosion resistance, bio-compatibility, and many other attributes important to a wide range of applications. Some of these applications include hard coatings for cutting tools and wear parts, high-strength ceramics, adaptive coatings for military and industrial applications, improved implant surfaces for medical and dental implants, and other applications that are only now emerging in this rapidly expanding field.

Duralor
Duralor.com
NanoMech's subsidiary, Duralor, is producing high performance coatings and coating processes for cutting tools and machine wear parts. Duralor’s award winning technology, exclusively licensed from NanoMech, LLC, includes the TuffTeK™ extreme wear resistant coating product line which provides a breakthrough increase in performance. TuffTeK™ coated tools can improve tool life 300% or more compared to conventional coatings, and will compete for a portion of the $20 billion global cutting tool market.



NanoWatt Design
NanoWattDesign.com
NanoWatt Design holds exclusive license to a patent-pending asynchronous circuit architecture that promises order-of-magnitude reductions in power consumption of digital circuitry, without sacrificing speed. The new Sleep Convention Logic (SCL) technology is fundamentally delay insensitive, overcoming timing issues with previous asynchronous architectures. In addition, the company will provide designers with software that allows industry-standard tools to be used in creating asynchronous SCL circuits. Overall, the technology is poised to become the most important integrated circuit design breakthrough of the decade.



Nutraceutical Innovations
Nutraceutical Innovations is developing applications of a patent pending process for value-added processing of rice bran and other food sources. The company is developing nutraceutical ingredients such as protein, phenolics and prebiotics that have numerous potential health benefits including antimutagenicity, anti-cancer properties and hypertension reduction.



SFC Fluidics
SFC-Fluidics.com
SFC Fluidics' mission is to provide unique microfluidic technologies that enable ever more powerful laboratories-on-a-chip, analytical tools, clinical diagnostics and life science research instruments. SFC Fluidics’ laboratory-on-a-chip devices are used with a highly portable readout instrument, and together they provide affordable, portable diagnostics capability with low operator skill requirement. This innovative technology has broad applications including automated detection of infectious and non-infectious disease and injuries.



TiFiber
TiFiber.com
TiFiber produces unique, thermally stable, chemically inert titanium dioxide nanofibers. These inorganic nanofibers can be used in a process analogous to making paper to craft free standing membranes. The free standing membranes possess unique porosity, permeability, thermal stability, chemical inertness, robustness, and catalytic activities, all of which differentiate TiFiber's material from monodispersed nanofibers and nanopowder. TiFiber nanofibers and membranes offer great performance advantages for high temperature filtration, catalysis, sensing, sorption, separation and many other large commercial applications.